A practical consideration on using the elixir on talismans
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When Crowley died, there were several talismans found in his effects that looked pretty messed up. So yeah, that's certainly possible.
I guess the lesson is that, in that particular system, having a talisman stay looking good wasn't as important as other things.
Consider that in VIII° work, some practices have you masturbating on your Enochian tablets. It is no surprise that, in time, these start... attracting things.